International Research Journal of Gastroenterology and Hepatology <p style="text-align: justify;"><strong>International&nbsp;&nbsp;Research Journal of Gastroenterology and Hepatology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/IRJGH/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Gastroenterology and Hepatology’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> en-US (International Research Journal of Gastroenterology and Hepa) (International Research Journal of Gastroenterology and Hepa) Fri, 10 Jan 2020 09:21:36 +0000 OJS 60 Functional Bowel Disorders, Psychosocial Correlates and Health-related Quality of Life in a Nigerian Community: Ilisan-Remo Functional Bowel Disorders Project Protocol <p><strong>Introduction</strong><strong>:</strong> Functional bowel disorders are functional gastrointestinal disorders affecting the middle or lower gastrointestinal tract. They occur worldwide and manifest with features of abdominal pain, bloating, distention, and/or bowel habit abnormalities such as diarrhea, constipation, or mixed diarrhea and constipation. Though benign, their interference with the patient’s daily activities constitutes a substantial socioeconomic burden. There is paucity of data concerning the functional bowel disorders and their psychosocial correlates, apart from irritable bowel syndrome, in Nigeria. More especially, these disorders have not been studied with the Rome IV iteration in the country. This study aims at bridging the observed gaps.&nbsp;</p> <p><strong>Materials and Methods</strong><strong>:</strong> The study shall be a descriptive cross-sectional community-based study. The study population shall consist of a cohort of 500 consenting adults aged 18 to 70 years who are residents of Ilisan-Remo, Ogun State, Nigeria. A composite questionnaire consisting of demographic data, medication history, the Rome IV Functional Bowel Disorder questionnaire, the Becks Anxiety, and Depression Inventories, the Pittsburgh Sleep Quality Index, the Early Trauma Inventory-Self Report, Short Form 12, version 2 Health Survey (SF-12v2) questionnaire and other relevant questions shall be used to obtain data from the participants. We shall analyze the data obtained with the IBM- Statistical Package for Social Sciences (SPSS), version 22.</p> <p><strong>Discussion</strong><strong>:</strong> The present study would be the first study to investigate a group of FBDs in Nigerian community using the Rome IV criteria. The study would investigate the association between the FBDs and a comprehensive list of prospective risk factors which include anxiety, depression, early trauma exposure, sleep quality, abdominal obesity, cigarette smoking, alcohol consumption, coffee intake, and physical exercise in a Nigerian population. It would also evaluate the health-related quality of life in persons who suffer from the FBDs and help to create awareness of the diseases.</p> <p><strong>Conclusion:&nbsp;</strong>When completed, this study would provide vital information concerning the prevalence, risk factors and health-related quality of life of functional bowel disorders in a black African population.</p> Abiodun Christopher Jemilohun, Kolowole Oluseyi Akande, Olufunke Oluwatosin Adeleye, Charles John Elikwu, Oluwatoyin Adetutu Fasesan, Theophilus Oludare Ajiro ##submission.copyrightStatement## Fri, 10 Jan 2020 00:00:00 +0000 Chemical Content and Antioxidant Potential of Aqueous Extract of Irish Potato Tubers Traditionally Used for Ulcer Treatment in Nigeria <p><strong>Aim:</strong> The study evaluated the chemical contents and antioxidant potential of aqueous extract of Irish potato tubers traditionally used for ulcer treatment in Nigeria.</p> <p><strong>Methods:</strong> Freshly harvested Irish potato tubers were purchased from Aba grocery market, Abia State. They were thoroughly washed in running water, peeled, sliced and dried in an oven at 60ºC to a constant weight. The dried potatoes were milled into fine powder (flour) and extracted using water as the solvent. The proximate, mineral, phytochemical and vitamin contents as well as antioxidant potentials were determined using standard methods.</p> <p><strong>Results:</strong> The results of the proximate analysis showed that the extract contain high percentage of carbohydrate (76.39±4.06%) followed by crude fat (11.43±0.75%) while crude protein (0.82±0.07%) is the least nutritional composition.&nbsp; Magnesium, sodium and iron contents are high in the extract, but calcium and copper were absent. The extract also contain high amounts of phenols (15.54±0.21%), flavonoids (13.03±1.59%), saponins (8.09±0.43%) and alkaloids (4.46±0.91%), but low in antinutrients. Total antioxidant capacity of the extract was 40.16±1.25 mg/AAE/g, with vitamins A, C and E contents being 3.56±0.01 mg/100 g, 61.78±12.48 mg/100 g and 20.39±0.11 µg/100 g respectively.</p> <p><strong>Conclusion:</strong> The results of the present study indicate that Irish potato tubers have high phytochemical content and possess antioxidant potential substantiating its use traditionally in the treatment of stomach ulcers.</p> U. Ogbuagu, C. U. Igwe, L. A. Nwaogu, A. I. Airaodion, E. O. Ogbuagu ##submission.copyrightStatement## Sat, 11 Jan 2020 00:00:00 +0000 Duplex Color Doppler Measurement of Hepatic Artery Resistance Index in Evaluation of Severity of Hepatic Steatosis <p><strong>Aims: </strong>The present study aims to highlight the duplex color doppler measurement of hepatic artery resistance Index in Evaluation of Severity of Hepatic Steatosis.</p> <p><strong>Introduction:</strong> This study was conducted to evaluate the correlation between the severity of fatty liver and the hepatic artery resistance index.</p> <p><strong>Methodology:</strong> A cross-sectional study was conducted in Radiology and Imaging Department, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) among 172 respondents. Purposive sampling technique was applied to select respondents who referred to Radiology and Imaging Department of BIRDEM for ultrasonogram of the upper abdomen and showed fatty infiltration. Fatty infiltration of liver was graded sonographically. The resistance index calculated for each patient was the mean of 3 measurements. Mean resistance index of the hepatic artery was then calculated for each group.</p> <p><strong>Results:</strong> In case of grade 1 (G1) hepato-steatosis patient’s Resistance index (RI) ranges from 0.76-0.85 (mean: 0.78 ± 0.02), grade 2 (G2) hepato-steatosis patient’s Resistance index (RI) ranges from 0.72-0.75 (mean: 0.74 ± 0.01) and grade 3 (G3) hepato-steatosis patient’s Resistance index (RI) ranges from 0.61-0.71 (mean: 0.68 ± 0.03). By hepatic steatosis we mean the abnormal accumulation of fat within the hepatocytes. It is benign as well as reversible condition and most patients are asymptomatic. And usually, if untreated it may progress to steatohepatitis and eventually to cirrhosis.</p> <p><strong>Conclusion:</strong> Hepatic artery resistance index (RI) decreases as the severity of diffuse fatty infiltration increases.</p> M. N. Rubaia Islam Bony, Md. Ubaidul Islam, Parbati Devnath, Nahid Safrin, Mahbuba Azim Moonmoon ##submission.copyrightStatement## Sat, 25 Jan 2020 00:00:00 +0000