Chemical Content and Antioxidant Potential of Aqueous Extract of Irish Potato Tubers Traditionally Used for Ulcer Treatment in Nigeria

Main Article Content

U. Ogbuagu
C. U. Igwe
L. A. Nwaogu
A. I. Airaodion
E. O. Ogbuagu

Abstract

Aim: The study evaluated the chemical contents and antioxidant potential of aqueous extract of Irish potato tubers traditionally used for ulcer treatment in Nigeria.

Methods: Freshly harvested Irish potato tubers were purchased from Aba grocery market, Abia State. They were thoroughly washed in running water, peeled, sliced and dried in an oven at 60ºC to a constant weight. The dried potatoes were milled into fine powder (flour) and extracted using water as the solvent. The proximate, mineral, phytochemical and vitamin contents as well as antioxidant potentials were determined using standard methods.

Results: The results of the proximate analysis showed that the extract contain high percentage of carbohydrate (76.39±4.06%) followed by crude fat (11.43±0.75%) while crude protein (0.82±0.07%) is the least nutritional composition.  Magnesium, sodium and iron contents are high in the extract, but calcium and copper were absent. The extract also contain high amounts of phenols (15.54±0.21%), flavonoids (13.03±1.59%), saponins (8.09±0.43%) and alkaloids (4.46±0.91%), but low in antinutrients. Total antioxidant capacity of the extract was 40.16±1.25 mg/AAE/g, with vitamins A, C and E contents being 3.56±0.01 mg/100 g, 61.78±12.48 mg/100 g and 20.39±0.11 µg/100 g respectively.

Conclusion: The results of the present study indicate that Irish potato tubers have high phytochemical content and possess antioxidant potential substantiating its use traditionally in the treatment of stomach ulcers.

Keywords:
Antioxidant capacity, peptic ulcer, Solanum tuberosum, phytochemical content.

Article Details

How to Cite
Ogbuagu, U., Igwe, C. U., Nwaogu, L. A., Airaodion, A. I., & Ogbuagu, E. O. (2020). Chemical Content and Antioxidant Potential of Aqueous Extract of Irish Potato Tubers Traditionally Used for Ulcer Treatment in Nigeria. International Research Journal of Gastroenterology and Hepatology, 3(1), 10-18. Retrieved from http://journalirjgh.com/index.php/IRJGH/article/view/30109
Section
Original Research Article

References

Okonkwo JC, Ene LS, Okoli OO. Potato production in Nigeria. National Root Crops Research Institute, Umudike, Umuahia, Abia State, Nigeria. 1995;1-109.

National Root Crops Research Institute (NRCRI). Research Highlight N.R.C.R.I Umudike. Account; 2005.

Okunade SO, Ibrahim MH. Assessment of the evaporative cooling system for storage of Irish potato. Journal of Production Agriculture and Technology of Nassarawa State University, Keffi. 2011;7(1):74-83.

Kudi TM, Apoko IG, Yada P. Resource Productivity Profitability Analysis of Irish Potato; 2008.

Hasler CM, Blumberg JB. Symposium on phytochemicals: Biochemistry and physiology. Journal of Nutrition. 1999;129: 756S-757S.

Mathai K. Nutrition in the Adult Years. In: Krause’s food, nutrition and diet therapy. 10th ed. Mahan LK, Escott-Stump S. 2000;271:274-275.

Airaodion AI, Olatoyinbo PO, Ogbuagu U,Ogbuagu EO, Akinmolayan JD, Adekale OA, Awosanya OO, Agunbiade AP, Oloruntoba AP, Obajimi OO, Adeniji AR, Airaodion EO. Comparative assessment of phytochemical content and antioxidant potential of Azadirachta indica and Parquetina nigrescens leaves. Asian Plant Research Journal. 2019;2(3):1-14.

Airaodion AI, Ibrahim AH, Ogbuagu U, Ogbuagu EO, Awosanya OO, Akinmolayan JD, Njoku OC, Obajimi OO, Adeniji AR, Adekale OA. Evaluation of phytochemical content and antioxidant potential of Ocimum gratissimum and Telfairia occidentalis leaves. Asian Journal of Research in Medical and Pharmaceutical Sciences. 2019;7(1):1-11.

Zakaria NA, Ibrahim D, Sulaiman SF, Supardy A. Assessment of antioxidant activity, total phenolic content and in-vitro toxicity of Malaysian red seaweed, Acanthophora spicifera. J. Chem. Pharm. Res. 2011;3:182-191.

Halliwell B, Gutteridge JC. The definition and measurement of antioxidants in biological systems. Free Radic Biol Med. 1995;18:125–6.

Young IS, Woodside JV. Antioxidants in health and disease. J Clin Pathol. 2001; 54:176–186.

AOAC. Association of Official Analytical Chemists. Official Methods of Analysis 18th edition. Washington DC, USA; 2010.

Williams RR. Atomic absorption spectroscopy. Anal. Chem. 1991;63:1638.

Rajeev S, Pawan KV, Gagandeep S. Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium. J Intercult Ethnopharmacol. 2012;1(2):101-104.

Onwuka GI. Food analysis and instrumentation (Theory and practice). 1st edn, Napthali prints, Surulere, Lagos – Nigeria. 2005;140-160.

Ejikeme CM, Ezeonu CS, Eboatu AN. Determination of physical and phytochemical constituents of some tropical timbers indigenous to Niger Delta Area of Nigeria. European Scientific Journal. 2014;10(18):247–270.

Harborne IB. Phytochemical methods: A guide to modern techniques of plant analysis. 2nd Edition, Chapman and Hall, New York. 1973;88-185.

Prieto P, Pineda M, Aguilar M. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: Specific application to the determination of vitamin E. Analytical Biochemistry. 1999; 269:337–341.

Rutkowski M, Grzegorczyk K. Modifications of spectrophotometric methods for antioxidative vitamins determination convenient in analytic practice. Acta Sci. Pol. Technol. Aliment. 2007;6(3):17-28.

Sari H, Sirpa OK, Marina IH, Hannu MM, Riitta AT. Content of the flavanolsquercetin, myricetin and kaemferol in 25 edible berries. J Agri Food Chem. 1999;47:2274–2279.

Sumbul S, Ahmad MA, Mohd A, Mohd A. Role of phenolic compounds in peptic ulcer: An overview. J Pharm Bioallied Sci. 2011;3:361-367.

Airaodion AI, Airaodion EO, Ewa O, Ogbuagu EO, Ogbuagu U. Nutritional and anti–nutritional evaluation of garri processed by traditional and instant mechanical methods. Asian Food Science Journal. 2019;9(4):1-13.

Lewu MN, Adebola PO, Afolayan AJ. Comparative assessment of the nutritional value of commercially available cocoyam and potato tubers in South Africa. Journal of Food Quality. 2009;33(2010):461– 476.

Arukwe U, Amadi BA, Duru MKC, Agomuo EN, Adindu EA, Odika PC, Lele KC, Egejuru L, Anudike J. Chemical composition of Persea americana leaf, fruit and seed. International Journal of Recent Research and Applied Studies. 2012;11 (2):346-349.

Wekesa MN, Okoth MW, Abong GO, Muthoin J, Kabira JN. Effect of soil characteristics on potato tuber minerals composition of selected Kenyan varieties. Journal of Agricultural Science. 2014;6 (12):163-171

Carriaga TM, Skikne BS, Finley B, Cutler B, Cook J. Serum transferring receptor for the detection of iron deficiency in pregnancy. American Journal of Clinical Nutrition. 1991;54:1077-1081.

Paul SH, Jacob SO, Usman AA, Auta M, Olutoye MA. Development and characterisation of a multifunctional hybrid nano-flora composite for the prevention and management of cancer, diabetes, blood pressure and stroke. Eng. Technol. Open Acc. 2018;1(1):1-17.

Zhang W, Wu X, Niu J, Yan H, Wang X, Yin X, Pang Y. Serum zinc status and helicobacter pylori infection in gastric disease patients. Asian Pacific J. Cancer Prev. 2012;13(10):5043-5046.

Matsukura T, Tanaka H. Applicability of zinc complex of Lcarnosine for medical use. Biochemistry (Moscow). 2000;65:817-823.

Liu J, Ma L. The protective activity of Conyzablinii saponin against acute gastric ulcer induced by ethanol. J Ethnopharmacol. 2014;158:358-363.

Friedman M. Chemistry, biochemistry, and dietary role of potato polyphenols. A review. Journal of Agricultural and Food Chemistry. 1997;45:1523–1540.

Narayan S, Devi RS, Srinivasan P, Devi CS. Pterocarpus santalinus: A traditional herbal drug as a protectant against ibuprofen induced gastric ulcers. Phytother Res. 2005;19:958-962.

Brown C, Wrolstand R, Clevidence B. Breeding potatoes with high antioxidant values. Proceedings of the Washington State Potato Conference; 2001.

Airaodion AI, Obajimi OO, Ezebuiro CN, Ogbuagu U, Agunbiade AP, Oloruntoba AP, Akinmolayan JD, Adeniji AR, Airaodion EO. Prophylactic efficacy of aqueous extract of Curcuma longa leaf against indomethacin-induced ulcer. International Journal of Research. 2019;6(1):87-91.

Airaodion AI, Ogbuagu U, Ogbuagu EO, Airaodion EO, Agunbiade AP, Oloruntoba AP, Mokelu IP, Ekeh SC. Investigation of aqueous extract of Zingiber officinale root potential in the prevention of peptic ulcer in albino rats. International Journal of Research and Innovation in Applied Science. 2019;4(2):64-67.

Airaodion AI, Olayeri IM, Ewa AO, Ogbuagu EO, Ogbuagu U, Akinmolayan JD, Agunbiade AP, Oloruntoba AP, Airaodion EO, Adeniji AR, Obajimi OO, Awosanya OO. Evaluation of Moringa oleifera leaf potential in the prevention of peptic ulcer in wistar rats. International Journal of Research. 2019;6(2):579-584.

Bahramsoltani R, Farzaei MH, Rahimi R. Medicinal plants and their natural components as future drugs for the treatment of burn wounds: An integrative review. Arch Dermatol Res. 2014;306: 601-617.

Agoreyo BO, Obansa ES, Obanor EO. Comparative nutritional and phytochemical analyses of two varieties of Solanum melongena. Science World Journal. 2012;7:5-8.

Repetto MG, Llesuy SF. Antioxidant properties of natural compounds used in popular medicine for gastric ulcers. Braz J Med Biol Res. 2002;35:523-534

Ito N, Hirose M, Imaida K. Antioxidants: Carcinogenic and chemopreventive properties. In: Bertino JR, editor. Encyclopedia of Cancer, Vol. 1, California, Academic Press. 2006;51–63.

Almasaudi SB, El-Shitany NA, Abbas AT, Abdel-Dayem UA, Ali SS, Jaouni SK. Antioxidant, anti-inflammatory and antiulcer potential of manuka honey against gastric ulcer in rats. Oxid Med Cell Longev. 2016;364-382.

Cotton PA, Subar AF, Friday JE, Cook A. Dietary sources of nutrients among US adults. Journal of American Dietary Association. 2004;104:921-930.

Dinda B, SilSarma I, Dinda M, Rudrapaul P. Oroxylumindicum L. an important Asian traditional medicine: From traditional uses to scientific data for its commercial exploitation. J Ethnopharmacol. 2015;161: 2555-2578.

Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: A review of preclinical and clinical research. Altern Med Rev. 2009;14: 141-153.

Mishra V, Agrawal M, Onasanwo SA, Madhur G, Rastogi P, Pandey HP. Anti-secretory and cytoprotective effects of chebulinic acid isolated from the fruits of Terminalia chebula on gastric ulcers. Phytomedicine. 2013;20:506–511.

Farzaei MH, Rahimi R, Abbasabadi Z, Abdollahi M. An evidence based review on medicinal plants used for the treatment of peptic ulcer in traditional Iranian medicine. Int J Pharmacol. 2013;9:108-124.

Bader A, Braca A, De Tommasi N, Morelli I. Further constituents from Caralluma negevensis. Phytochemistry. 2003;62: 1277–1281.